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Integrins are transmembrane proteins that interact with the ECM to link the extracellular surroundings towards the intracellular cytoskeleton.
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Thus, our data show the Pro32Pro33 KI mouse design, Irrespective of not currently being a fully humanized allele, replicates the phenotypes noticed in the human Pro33 platelets.
4F). We then examined whether the raises in pSrc concentrations in KI platelets final result from enhanced Src associations Using the β
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